Timeless TCID50: One solution to many viruses
This month we cover an old classic, the Tissue Culture Infectious Dose 50 assay, or TCID50. The TCID50 assay is used to quantify viral titres by determining the concentration at which 50% of the infected cells display cytopathic effect (CPE). As long as the virus of...
A small-molecule that mimicks anti-flu antibodies
A small-molecule that mimicks anti-flu antibodies Flu is a serious health problem: what are we doing about it? Flu makes millions of people ill and kills hundreds of thousands every year. At the moment, seasonal flu vaccines are the best available defence against...
High-throughput/high-content virology and screening
High-throughput/high-content virology and screening In the past decade, high-throughput screening has become a critical tool in antiviral discovery. More recently, advances in high-throughput and high-content imaging have further advanced unbiased phenotypic...
The virus of the month: RSV
The virus of the month: RSV With about 34 million infections per year, 10% of which require hospitalization, respiratory syncytial virus (RSV) is the most common cause of annual winter lower respiratory tract infections. While for young healthy adults RSV causes mild...Page 16 of 30